Survival of Bacteriophage T4 in Quasi-Pure Ionic Solutions

نویسندگان

چکیده

The preservative qualities of individual ionic compounds impacting the infectivity T4 virions were elucidated. immersed in quasi-pure solutions prior to adsorption process, and plaque forming unit (pfu) values these measured following conventional method. In neutral solutions, minimum optimum concentrations corresponded with results obtained from multi-ionic media/buffers. acid alkali phages show tolerances at a pH range 5–11 no tolerance acid, neutral, weak alkaline conditions. quality increased over 10−1 mM OH− solution, equivalent value 10, which corresponds pKa deprotonation DNA bases G T. Infectivity was lost below higher than 10 OH−. These imply that maintaining virion may need flexibility intra-capsid by deprotonation.

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ژورنال

عنوان ژورنال: Viruses

سال: 2023

ISSN: ['1999-4915']

DOI: https://doi.org/10.3390/v15081737